Oral Fenbendazole for Cancer Therapy in Humans and Animals
Fenbendazole is a benzimidazole anthelmintic agent commonly used to treat animal parasitic infections. In humans, other benzimidazoles, such as mebendazole and albendazole, are used as antiparasitic agents. Since fenbendazole is not currently approved by the FDA or EMA, its pharmacokinetics and safety in humans have yet to be well-documented in medical literature. Despite this, insights can be drawn from existing in vitro and in vivo animal studies on its pharmacokinetics. Given the low cost of fenbendazole, its high safety profile, accessibility, and unique anti-proliferative activities, fenbendazole would be the preferred benzimidazole compound to treat cancer. To ensure patient safety in the repurposing use of fenbendazole, it is crucial to perform clinical trials to assess its potential anticancer effects, optimal doses, therapeutic regimen, and tolerance profiles. This review focuses on the pharmacokinetics of orally ...
The New York Stock Exchange (NYSE) has officially announced the launch of $RLUSD, Ripple's enterprise-grade stablecoin! 🌟💵
This move underscores the growing institutional adoption of blockchain-powered financial solutions. 🚀💼 Stay tuned for more updates on how $RLUSD is set to transform the global payments landscape! 🌐✨
😲
US Senator Bill Hagerty and his Republican colleagues have rejected the reassignment of SEC Commissioner Caroline Crenshaw, who is known for her anti-crypto stance and close alliance with Gary Gensler. 🪙⚖️
This decision underscores the ongoing debates and concerns within the crypto community regarding SEC regulations and the future of cryptocurrency in the U.S. 🔍📉
Custom AI assistants that print money in your sleep? 🔜
The future of Crypto x AI is about to go crazy.
👉 Here’s what you need to know:
💠 'Based Agent' enables creation of custom AI agents
💠 Users set up personalized agents in < 3 minutes
💠 Equipped w/ crypto wallet and on-chain functions
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💠 Integrates with Coinbase’s SDK, OpenAI, & Replit
👉 What this means for the future of Crypto:
1. Open Access: Democratized access to advanced trading
2. Automated Txns: Complex trades + streamlined on-chain activity
3. AI Dominance: Est ~80% of crypto 👉txns done by AI agents by 2025
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According to insider sources, President Donald Trump is exploring the creation of a national crypto reserve featuring Made-in-America cryptos like XRP, HBAR, alongside BTC. 🪙
🚀 Big vision: XRP could potentially become the U.S. Digital Reserve Currency!
Stay tuned for more updates on this bold move. 🌟
Sonic is live! Sonic is a new Layer-1 network developed by the team behind Fantom, including Andre Cronje. The road to Sonic began with a series of four Fantom governance proposals between May and July and culminated yesterday when mainnet went live. A core feature of Sonic is Fee Monetization (FeeM). FeeM allows protocols approved by governance to capture transaction fees generated by their application. Transactions fall under two categories:
FeeM: Transaction fees generated by FeeM protocols will be distributed as follows; 90% to the protocol and 10% to validators.
Non-FeeM: Transaction fees generated by non-FeeM protocols will be distributed as follows: 50% burned, 45% to validators, and 5% to the Ecosystem Vault.
FTM is S. Testnet campaigns (Road to Sonic, Sonic Boom, Sonic Arcade) generated hype and provided ways to earn points and gems before yesterday’s launch. Now, tokenholders can now convert FTM to S at a 1:1 ratio. Alongside the new token comes a reimagining of tokenomics. The token will now become inflationary, highlighted by 190.5 million S (6% of the initial supply) being minted for airdrops over the next two years.
The airdrop allocation is worth $221 million. While specific details are yet to be announced, historic Fantom users and new Sonic users will be eligible. Fantom ended with a TVL of $136 million. Less than a day after launch, Sonic’s TVL sits at $3.7 million. Users and capital are flowing in as airdrop farming begins.
Fantom hasn’t been top of mind. A major rebrand, relaunch, and tokenomics update provides another shot on goal. A chance to reinvigorate the ecosystem and onboard net new capital and users. This trickles down to applications too. Beethoven X, a Fantom-native DEX, is rebranding to Beets as it shifts strategy to focus on liquid-staked S (stS) and a DAO-managed validator.
Competition is tough. Can Sonic compete for users, assets, and mindshare from the crowd of new networks like Hyperliquid, MegaETH, Eclipse, Monad, Berachain, and Ink? Time will tell.
There aren’t yet a huge number of regulated venues for security tokens, but Singapore based AsiaNext is one of them. This month it listed its first tokenized security, a USD money market fund (MMF), and launched a novel digital collateral solution.
AsiaNext was founded as a joint venture between Switzerland’s SIX and Japan’s SBI Holdings. Both companies have a pedigree with digital securities secondary markets in SDX and ODX respectively. However, AsiaNext first launched with crypto derivatives at the start of this year. They don’t require a license in Singapore.
That’s the first of three trading offerings, which is highly relevant because the collateral solution allows collateral from one area to be used in others.
The company holds a Singapore capital markets license and another as a recognized market operator (RMO), which allows it to operate a digital exchange. The MMF is the first digital securities listing. It is working with asset managers to list other funds, including Valour a multinational crypto ETP issuer with $900 million in assets under management.
AsiaNext is also planning a third trading venue for spot crypto trading and has applied for a Major Payments Institution license.
In the meantime, it has launched the AsiaNext Orchestration Layer (AXOL) which integrates the three trading venues. Given derivatives trading usually works on margin, the collateral that institutions can post could be fiat currency, stablecoins, crypto or digital securities. Those could all come from one of the three trading venues, enabling capital efficiency. AXOL uses workflows to streamline the collateral management and members can also earn yield on their assets.
Our launch of the AsiaNext Orchestration Layer is a bold step into the future of institutional crypto trading,” said Neil Thomas, Chief Commercial Officer at AsiaNext. “By combining the power of blockchain technology with tried and tested finance principles, we are giving our members the edge they need to thrive in an increasingly complex trading environment”
Meanwhile, earlier this year AsiaNext collaborated with Malaysian digital assets platform, KLDX, which focuses on private equity and debt. Through the collaboration they plan to offer a wider range of investments and improve liquidity.
One of AsiaNext’s affiliates, SBI Digital Markets, is also working with new EU exchange 21X to list products in Europe.
China has imprisoned two men for using the Tether stablecoin (USDT) to circumvent foreign exchange controls. They received five year sentences after processing RMB 30 million ($4.1m) in transactions.
One of the traders met a Nigerian online who complained about the foreign exchange costs of converting naira to renminbi. So Lin, the Chinese trader, came up with a plan for the Nigerian, ‘Prince’, to buy Tether on a local crypto exchange and transfer it to Lin. He then sold the Tether to domestic currency dealers, deposited the renminbi into a local bank and transferred it to an account belonging to Prince. After making 300 yuan on the first transaction, Lin went into business with a friend, Yan.
Within months their bank accounts were restricted because of large fund inflows of RMB 21 million ($2.9 m) so they co-opted a third person Xie to provide a bank card to receive funds. They continued at a slower pace until their arrest in June 2022. The authorities collected evidence including WeChat chat records, bank transactions and records from overseas crypto trading platforms, which resulted in the three pleading guilty. Lin and Yan were imprisoned for five years, with Xie receiving a 1.5 year suspended sentence.
Stepping back, the timing of this coincides with the Nigerian government taking action against Binance Nigeria and other cryptocurrency exchanges. The prosecution of the Chinese traders started on February 26 and presumably involved some interaction with Nigerian authorities. Nigeria started taking steps against crypto exchanges in the first week of March. The timing could be a coincidence because Nigeria blamed the crypto exchanges for the plunging value of the Naria from late January to early March this year.
Meanwhile, the Chinese state appears to be using the case as a lesson to others, because multiple news outlets, including Sina, described why it is an offense. A major issue for China is that it circumvents foreign currency controls. Specifically, they want to control Chinese money flowing out, which wasn’t the case here. The authorities also want to keep tabs on inward investment and manage the exchange rate. Secondly, they’re concerned that circumvention leads to inaccurate economic data. What’s not mentioned is that legitimate cross border trading without FX tracking would make tax evasion easier. Plus, there are the usual worries about money laundering by criminals.
In 2022, the International Monetary Fund (IMF) published a paper exploring the cryptocurrency challenges to capital controls.
